The research aims at the characterization and understanding of the molecular mechanisms that can explain the response of cellular organelles and prokaryotic systems involved in energy transduction, to different conditions of stress.
The research activities concern expression, structure and assembly of membrane energy transducing systems of both prokaryotes and eukaryotes. Structural and functional relationships of OXPHOS complexes.
It is involved in the identification and in the functional and structural characterization of mitochondrial membrane transporters belonging to the family SLC25 known as "mitochondrial carrier family (MCF)".
Objective of the research is the study of signaling pathways and mitochondrial metabolism in different models of neurodegenerative/neurodevelopmental diseases and in cancer.
Despite the great advances in biological research in recent years, we still have a very limited knowledge of the wide variety of species that inhabit the earth in its various environments, and their dynamics in relation to different ecosystems, environmental pollution and climate changes.
Bobba A, Amadoro G, La Piana G, Petragallo VA, Calissano P, Atlante A.
Description: Mitozoa is a database resource and search tools for comparative and evolutionary analyses of mitochondrial genomes in Metazoa